Version 5.4
Homo sapiens Gene: NDNL2
Summary
InnateDB Gene IDBG-4670.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NDNL2
Gene Name necdin-like 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185115
Encoded Proteins
IDBP-4672
necdin-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. [provided by RefSeq, May 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:29268149-29269829
Strand Reverse strand
Band q13.1
Transcripts
ENST00000332303 ENSP00000330694
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0031398 positive regulation of protein ubiquitination
GO:0040008 regulation of growth
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030915 Smc5-Smc6 complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000070520
View Gene Order
ENSBTAG00000039634
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
p75ntrpathway
p75(NTR)-mediated signaling
Cross-References
SwissProt Q96MG7
TrEMBL
UniProt Splice Variant
Entrez Gene 56160
UniGene Hs.732214
RefSeq NM_138704
HUGO HGNC:7677
OMIM 608243
CCDS CCDS10023
HPRD 10503
IMGT
EMBL AF320911 AF490510 AK056957 AK074138 BC041166 BC053999
GenPept AAG38607 AAH41166 AAH53999 AAM08357 BAB71325 BAB84964
RNA Seq Atlas 56160

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca