Homo sapiens Gene: KRT20
Summary
InnateDB Gene IDBG-48325.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT20
Gene Name keratin 20
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171431
Encoded Proteins
keratin 20
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:40875941-40885227
Strand Reverse strand
Band q21.2
Transcripts
ENST00000167588 ENSP00000167588
ENST00000482529
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 18 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
Biological Process
GO:0006915 apoptotic process
GO:0033554 cellular response to stress
GO:0045109 intermediate filament organization
GO:0050708 regulation of protein secretion
Cellular Component
GO:0005737 cytoplasm
GO:0005882 intermediate filament
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.84905
RefSeq NM_019010
HUGO
OMIM
CCDS CCDS11379
HPRD 12193
IMGT
EMBL
GenPept
RNA Seq Atlas