Version 5.4
Homo sapiens Gene: SPIRE2
Summary
InnateDB Gene IDBG-48448.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPIRE2
Gene Name spire homolog 2 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000204991
Encoded Proteins
IDBP-48450
spire homolog 2 (Drosophila)
IDBP-244389
spire homolog 2 (Drosophila)
IDBP-751002
IDBP-754629
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 16:89818179-89871319
Strand Forward strand
Band q24.3
Transcripts
ENST00000378247 ENSP00000367494
ENST00000393062 ENSP00000376782
ENST00000565103
ENST00000563972 ENSP00000457940
ENST00000565628
ENST00000562029
ENST00000561883
ENST00000564878
ENST00000569108
ENST00000566337 ENSP00000457981
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0030036 actin cytoskeleton organization
GO:0036089 cleavage furrow formation
GO:0040038 polar body extrusion after meiotic divisions
GO:0046907 intracellular transport
GO:0051295 establishment of meiotic spindle localization
GO:0070649 formin-nucleated actin cable assembly
Cellular Component
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0030659 cytoplasmic vesicle membrane
GO:0032154 cleavage furrow
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000010154
View Gene Order
ENSBTAG00000040356
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04320
Dorso-ventral axis formation pathway
INOH
PID NCI
Cross-References
SwissProt Q8WWL2
TrEMBL B3KT42 H3BV39 H3BV74
UniProt Splice Variant
Entrez Gene 84501
UniGene Hs.461786 Hs.734199
RefSeq NM_032451 XM_006721302 XM_006721303 XM_006721304 XM_006721307
HUGO HGNC:30623
OMIM 609217
CCDS CCDS32516
HPRD
IMGT
EMBL AB058735 AC092385 AJ422077 AK094918 AL834408 BC063706 BC111030 BC139732
GenPept AAH63706 AAI11031 AAI39733 BAB47461 BAG52954 CAD19439 CAD39070
RNA Seq Atlas 84501

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca