Version 5.4
Homo sapiens Gene: PATL1
Summary
InnateDB Gene IDBG-48482.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PATL1
Gene Name protein associated with topoisomerase II homolog 1 (yeast)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000166889
Encoded Proteins
IDBP-48484
protein associated with topoisomerase II homolog 1 (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:59636716-59668980
Strand Reverse strand
Band q12.1
Transcripts
ENST00000300146 ENSP00000300146
ENST00000531919
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0008266 poly(U) RNA binding
GO:0034046 poly(G) binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0010467 gene expression
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0033962 cytoplasmic mRNA processing body assembly
GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005829 cytosol
GO:0016605 PML body
GO:0016607 nuclear speck
GO:0030014 CCR4-NOT complex
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000046139
View Gene Order
ENSBTAG00000005913
Not yet available
Pathways
NETPATH
REACTOME
REACT_20518
mRNA decay by 5' to 3' exoribonuclease pathway
REACT_20639
Deadenylation-dependent mRNA decay pathway
REACT_71
Gene Expression pathway
KEGG
hsa03018
RNA degradation pathway
INOH
PID NCI
Cross-References
SwissProt Q86TB9
TrEMBL B3KXN0
UniProt Splice Variant
Entrez Gene 219988
UniGene Hs.591960 Hs.619558
RefSeq NM_152716 XM_005273833 XM_005273835
HUGO HGNC:26721
OMIM 614660
CCDS CCDS44613
HPRD
IMGT
EMBL AB065087 AK094193 AK127649 AK127943 AL831992 AP000442 AP000640 BC065264 BC109038 BC109039 BC111047
GenPept AAH65264 AAI09039 AAI09040 AAI11048 BAB93524 BAC04305 BAG54542 BAG54601 CAD89916
RNA Seq Atlas 219988

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca