Version 5.4
Homo sapiens Gene: GGN
Summary
InnateDB Gene IDBG-48739.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GGN
Gene Name gametogenetin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000179168
Encoded Proteins
IDBP-48743
gametogenetin
IDBP-763834
IDBP-765449
IDBP-764182
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:38384265-38388082
Strand Reverse strand
Band q13.2
Transcripts
ENST00000334928 ENSP00000334940
ENST00000587676 ENSP00000465186
ENST00000591809
ENST00000585737 ENSP00000467295
ENST00000586599 ENSP00000467084
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046983 protein dimerization activity
Biological Process
GO:0007275 multicellular organismal development
GO:0007276 gamete generation
GO:0007283 spermatogenesis
GO:0008104 protein localization
GO:0030154 cell differentiation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000031493
View Gene Order
ENSBTAG00000005363
Not yet available
Cross-References
SwissProt
TrEMBL K7EJI6
UniProt Splice Variant
Entrez Gene 199720
UniGene Hs.447948 Hs.739433
RefSeq NM_152657 XM_005258619
HUGO HGNC:18869
OMIM 609966
CCDS CCDS12516
HPRD 17036
IMGT
EMBL AC005789
GenPept
RNA Seq Atlas 199720

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca