Homo sapiens Gene: AGAP3
Summary
InnateDB Gene IDBG-49238.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AGAP3
Gene Name ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000133612
Encoded Proteins
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:151085831-151144436
Strand Forward strand
Band q36.1
Transcripts
ENST00000335367 ENSP00000335589
ENST00000397238 ENSP00000380413
ENST00000490097
ENST00000463381 ENSP00000418016
ENST00000473312 ENSP00000418921
ENST00000479901 ENSP00000418125
ENST00000469901 ENSP00000417151
ENST00000476375
ENST00000492234
ENST00000473140
ENST00000490839
ENST00000467724 ENSP00000419801
ENST00000468796 ENSP00000418159
ENST00000480106
ENST00000498559
ENST00000486946
ENST00000475145
ENST00000463179
ENST00000485904
ENST00000494808
ENST00000478320
ENST00000483971
ENST00000461065 ENSP00000417910
ENST00000467250
ENST00000473633
ENST00000622464 ENSP00000480655
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0031593 polyubiquitin binding
Biological Process
GO:0000060 protein import into nucleus, translocation
GO:0006184 GTP catabolic process
GO:0007165 signal transduction
GO:0007264 small GTPase mediated signal transduction
GO:0015031 protein transport
GO:0032312 regulation of ARF GTPase activity
GO:0034614 cellular response to reactive oxygen species
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0071944 cell periphery
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
Endocytosis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.647075
RefSeq NM_001042535 NM_001281300 NM_031946 XM_005249942
HUGO
OMIM
CCDS CCDS43681 CCDS55185 CCDS64802
HPRD 16707
IMGT
EMBL
GenPept
RNA Seq Atlas