Version 5.4
Homo sapiens Gene: KRT15
Summary
InnateDB Gene IDBG-49324.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KRT15
Gene Name keratin 15
Synonyms CK15; K15; K1CO
Species Homo sapiens
Ensembl Gene ENSG00000171346
Encoded Proteins
IDBP-49326
keratin 15
IDBP-242535
keratin 15
IDBP-242537
keratin 15
IDBP-378125
keratin 15
IDBP-763476
IDBP-762632
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:41513743-41522529
Strand Reverse strand
Band q21.2
Transcripts
ENST00000254043 ENSP00000254043
ENST00000393976 ENSP00000377546
ENST00000393974 ENSP00000377544
ENST00000458290 ENSP00000409282
ENST00000474031
ENST00000463447
ENST00000497016 ENSP00000466687
ENST00000470004 ENSP00000467875
ENST00000586794
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 61 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 61 [view]
Protein-Protein 61 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0097110 scaffold protein binding
Biological Process
GO:0008544 epidermis development
Cellular Component
GO:0005634 nucleus
GO:0005882 intermediate filament
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054146
View Gene Order
ENSBTAG00000004903
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.654570
RefSeq NM_002275 XM_005257345
HUGO
OMIM
CCDS CCDS11398
HPRD 01009
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca