InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KRT15

Summary

InnateDB Protein

IDBP-242535.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KRT15

Protein Name

keratin 15

Synonyms

CK15; K15; K1CO;

Species

Homo sapiens

Ensembl Protein

ENSP00000377546

InnateDB Gene

IDBG-49324 (KRT15)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate. {ECO:0000269PubMed:10084315, ECO:0000269PubMed:2452170}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 61 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	61 [view]
Protein-Protein	61 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005200	structural constituent of cytoskeleton
GO:0005515	protein binding
GO:0097110	scaffold protein binding