Homo sapiens Gene: ZP1
Summary
InnateDB Gene IDBG-49417.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZP1
Gene Name zona pellucida glycoprotein 1 (sperm receptor)
Synonyms HEL163; OOMD;
Species Homo sapiens
Ensembl Gene ENSG00000149506
Encoded Proteins
zona pellucida glycoprotein 1 (sperm receptor)
zona pellucida glycoprotein 1 (sperm receptor)
zona pellucida glycoprotein 1 (sperm receptor)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. [provided by RefSeq, May 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:60867562-60875693
Strand Forward strand
Band q12.2
Transcripts
ENST00000278853 ENSP00000278853
ENST00000540908 ENSP00000441293
ENST00000537203
ENST00000542971
ENST00000543020
ENST00000620319 ENSP00000480463
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007338 single fertilization
GO:0007339 binding of sperm to zona pellucida
GO:0032504 multicellular organism reproduction
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0030141 secretory granule
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Pathways
NETPATH
REACTOME
Interaction With The Zona Pellucida pathway
Fertilization pathway
Reproduction pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 22917
UniGene Hs.172130
RefSeq NM_207341
HUGO HGNC:13187
OMIM 195000
CCDS CCDS31572
HPRD 15953
IMGT
EMBL
GenPept
RNA Seq Atlas 22917