Version 5.4
Homo sapiens Gene: ACTR3B
Summary
InnateDB Gene IDBG-50050.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACTR3B
Gene Name ARP3 actin-related protein 3 homolog B (yeast)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000133627
Encoded Proteins
IDBP-50052
ARP3 actin-related protein 3 homolog B (yeast)
IDBP-50056
ARP3 actin-related protein 3 homolog B (yeast)
IDBP-235721
ARP3 actin-related protein 3 homolog B (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility. Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:152759749-152855378
Strand Forward strand
Band q36.1
Transcripts
ENST00000256001 ENSP00000256001
ENST00000377776 ENSP00000367007
ENST00000397282 ENSP00000380452
ENST00000488782
ENST00000479402
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
GO:0005524 ATP binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0042995 cell projection
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056367
View Gene Order
ENSBTAG00000008032
Not yet available
Cross-References
SwissProt Q9P1U1
TrEMBL B3KM55 C9J580
UniProt Splice Variant
Entrez Gene 57180
UniGene Hs.647117
RefSeq NM_001040135 NM_020445 XM_006716064 XM_006716068
HUGO HGNC:17256
OMIM
CCDS CCDS34782 CCDS5934
HPRD
IMGT
EMBL AC005586 AC006008 AC072057 AC092180 AF023453 AF086920 AK001198 AK294292 AK315534 BC008682 BC015207
GenPept AAC98904 AAH08682 AAH15207 AAP97150 BAG37914 BAG50867 BAG57575
RNA Seq Atlas 57180

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca