Version 5.4
Homo sapiens Gene: RASSF2
Summary
InnateDB Gene IDBG-50172.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RASSF2
Gene Name Ras association (RalGDS/AF-6) domain family member 2
Synonyms CENP-34; RASFADIN
Species Homo sapiens
Ensembl Gene ENSG00000101265
Encoded Proteins
IDBP-50174
Ras association (RalGDS/AF-6) domain family member 2
IDBP-50178
Ras association (RalGDS/AF-6) domain family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:4780023-4823645
Strand Reverse strand
Band p13
Transcripts
ENST00000379400 ENSP00000368710
ENST00000379376 ENSP00000368684
ENST00000478553
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 46 experimentally validated interaction(s) in this database.
Experimentally validated
Total 46 [view]
Protein-Protein 46 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001501 skeletal system development
GO:0001503 ossification
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0038168 epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade
GO:0045667 regulation of osteoblast differentiation
GO:0045670 regulation of osteoclast differentiation
GO:0046849 bone remodeling
GO:0048872 homeostasis of number of cells
GO:1901222 regulation of NIK/NF-kappaB signaling
GO:1901223 negative regulation of NIK/NF-kappaB signaling
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027339
View Gene Order
ENSBTAG00000017346
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.631504
RefSeq NM_014737 NM_170774 XM_005260895 XM_006723668 XM_006723669
HUGO
OMIM
CCDS CCDS13083
HPRD 15218
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca