Version 5.4
Homo sapiens Gene: NCAPG2
Summary
InnateDB Gene IDBG-51142.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCAPG2
Gene Name non-SMC condensin II complex, subunit G2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146918
Encoded Proteins
IDBP-51146
non-SMC condensin II complex, subunit G2
IDBP-293622
non-SMC condensin II complex, subunit G2
IDBP-293620
non-SMC condensin II complex, subunit G2
IDBP-387647
non-SMC condensin II complex, subunit G2
IDBP-387648
non-SMC condensin II complex, subunit G2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPG2 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:158631311-158704829
Strand Reverse strand
Band q36.3
Transcripts
ENST00000356309 ENSP00000348657
ENST00000409423 ENSP00000386569
ENST00000409339 ENSP00000387007
ENST00000432615 ENSP00000414337
ENST00000441982 ENSP00000408080
ENST00000467785
ENST00000474940
ENST00000475918
ENST00000491792
ENST00000472591
ENST00000621338
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0035064 methylated histone binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0001833 inner cell mass cell proliferation
GO:0007067 mitotic nuclear division
GO:0030261 chromosome condensation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042029
View Gene Order
ENSBTAG00000016131
Not yet available
Pathways
NETPATH
REACTOME
REACT_172744
Condensation of Prophase Chromosomes pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_765
Mitotic Prophase pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.18616
RefSeq NM_001281932 NM_001281933 NM_017760
HUGO
OMIM
CCDS CCDS43686 CCDS64816
HPRD 10539
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca