Version 5.4
Homo sapiens Protein: NCAPG2
Summary
InnateDB Protein IDBP-51146.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCAPG2
Protein Name non-SMC condensin II complex, subunit G2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000348657
InnateDB Gene IDBG-51142 (NCAPG2)
Protein Structure
UniProt Annotation
Function Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. {ECO:0000269PubMed:14532007}.
Subcellular Localization Nucleus {ECO:0000269PubMed:14532007}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0035064 methylated histone binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007067 mitotic nuclear division
GO:0030261 chromosome condensation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR016024 Armadillo-type fold
IPR024741 Condensin-2 complex subunit G2
PFAM PF12422
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q86XI2
PhosphoSite PhosphoSite-Q86XI2
TrEMBL
UniProt Splice Variant
Entrez Gene 54892
UniGene Hs.18616
RefSeq NP_060230
HUGO HGNC:21904
OMIM 608532
CCDS CCDS43686
HPRD 10539
IMGT
EMBL AK022744 AK023347 BC005878 BC020560 BC043404 BX537845 CH236954
GenPept AAH05878 AAH20560 AAH43404 BAB14219 BAB14534 CAD97854 EAL23929

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca