Version 5.4
Homo sapiens Gene: GANAB
Summary
InnateDB Gene IDBG-51371.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GANAB
Gene Name glucosidase, alpha; neutral AB
Synonyms G2AN; GLUII
Species Homo sapiens
Ensembl Gene ENSG00000089597
Encoded Proteins
IDBP-51373
glucosidase, alpha; neutral AB
IDBP-51375
glucosidase, alpha; neutral AB
IDBP-596372
glucosidase, alpha; neutral AB
IDBP-600912
glucosidase, alpha; neutral AB
IDBP-599053
glucosidase, alpha; neutral AB
IDBP-599141
glucosidase, alpha; neutral AB
IDBP-596731
glucosidase, alpha; neutral AB
IDBP-597507
glucosidase, alpha; neutral AB
IDBP-599693
glucosidase, alpha; neutral AB
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:62624826-62646726
Strand Reverse strand
Band q12.3
Transcripts
ENST00000346178 ENSP00000340466
ENST00000356638 ENSP00000349053
ENST00000532402 ENSP00000432181
ENST00000528503
ENST00000534779 ENSP00000435306
ENST00000531563
ENST00000526732
ENST00000534422
ENST00000534613 ENSP00000434921
ENST00000525994 ENSP00000434805
ENST00000524437
ENST00000526210 ENSP00000433799
ENST00000526392
ENST00000529737 ENSP00000432593
ENST00000534419
ENST00000540933 ENSP00000442962
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 67 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 67 [view]
Protein-Protein 67 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0005515 protein binding
GO:0030246 carbohydrate binding
GO:0033919 glucan 1,3-alpha-glucosidase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006457 protein folding
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005788 endoplasmic reticulum lumen
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0017177 glucosidase II complex
GO:0042470 melanosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000071650
View Gene Order
ENSBTAG00000016956
Not yet available
Pathways
NETPATH
REACTOME
REACT_23810
Calnexin/calreticulin cycle pathway
REACT_23878
N-glycan trimming in the ER and Calnexin/Calreticulin cycle pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00510
N-Glycan biosynthesis pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q14697
TrEMBL
UniProt Splice Variant
Entrez Gene 23193
UniGene Hs.595071 Hs.706921
RefSeq NM_001278192 NM_001278193 NM_001278194 NM_198334 NM_198335
HUGO HGNC:4138
OMIM 104160
CCDS CCDS41656 CCDS60817 CCDS60818 CCDS8026
HPRD 03516
IMGT
EMBL AF144074 AJ000332 AP001458 BC017433 BC017435 BC065266 D42041
GenPept AAF66685 AAH17433 AAH17435 AAH65266 BAA07642 CAA04006
RNA Seq Atlas 23193

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca