Version 5.4
Homo sapiens Gene: INTS5
Summary
InnateDB Gene IDBG-51488.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTS5
Gene Name integrator complex subunit 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185085
Encoded Proteins
IDBP-51490
integrator complex subunit 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:62646848-62653302
Strand Reverse strand
Band q12.3
Transcripts
ENST00000330574 ENSP00000327889
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
Experimentally validated
Total 38 [view]
Protein-Protein 38 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032039 integrator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000071652
View Gene Order
ENSBTAG00000010455
Not yet available
Cross-References
SwissProt Q6P9B9
TrEMBL
UniProt Splice Variant
Entrez Gene 80789
UniGene Hs.458390
RefSeq NM_030628
HUGO HGNC:29352
OMIM 611349
CCDS CCDS8027
HPRD
IMGT
EMBL AB051485 BC028025 BC060841 BK005724
GenPept AAH28025 AAH60841 BAB21789 DAA05724
RNA Seq Atlas 80789

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca