Homo sapiens Gene: INTS5
Summary
InnateDB Gene IDBG-51488.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INTS5
Gene Name integrator complex subunit 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000185085
Encoded Proteins
integrator complex subunit 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:62646848-62653302
Strand Reverse strand
Band q12.3
Transcripts
ENST00000330574 ENSP00000327889
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
Experimentally validated
Total 38 [view]
Protein-Protein 38 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032039 integrator complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q6P9B9
TrEMBL
UniProt Splice Variant
Entrez Gene 80789
UniGene Hs.458390
RefSeq NM_030628
HUGO HGNC:29352
OMIM 611349
CCDS CCDS8027
HPRD
IMGT
EMBL AB051485 BC028025 BC060841 BK005724
GenPept AAH28025 AAH60841 BAB21789 DAA05724
RNA Seq Atlas 80789