Version 5.4
Mus musculus Gene: Ints5
Summary
InnateDB Gene IDBG-141528.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ints5
Gene Name integrator complex subunit 5
Synonyms 1110055N21Rik; mKIAA1698
Species Mus musculus
Ensembl Gene ENSMUSG00000071652
Encoded Proteins
IDBP-141530
integrator complex subunit 5
IDBP-788347
integrator complex subunit 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185085:
INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:8888926-8897890
Strand Forward strand
Band A
Transcripts
ENSMUST00000096249 ENSMUSP00000093968
ENSMUST00000191089 ENSMUSP00000140564
ENSMUST00000188635
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 35 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0016180 snRNA processing
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032039 integrator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000185085
View Gene Order
ENSBTAG00000010455
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 109077
UniGene
RefSeq NM_176843
OMIM
CCDS CCDS29556
HPRD
IMGT
MGI ID MGI:1923578
MGI Symbol Ints5
EMBL
GenPept
RNA Seq Atlas 109077

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca