Homo sapiens Gene: PROKR2
Summary
InnateDB Gene IDBG-51508.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PROKR2
Gene Name prokineticin receptor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000101292
Encoded Proteins
prokineticin receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:5302040-5314369
Strand Reverse strand
Band p12.3
Transcripts
ENST00000217270 ENSP00000217270
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004983 neuropeptide Y receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007623 circadian rhythm
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8NFJ6
TrEMBL
UniProt Splice Variant
Entrez Gene 128674
UniGene Hs.375029
RefSeq NM_144773 XM_005260663
HUGO HGNC:15836
OMIM 607123
CCDS CCDS13089
HPRD
IMGT
EMBL AB084081 AF506288 AL121755 BC104959 BC104961 EF577398
GenPept AAI04960 AAI04962 AAM48128 ABQ52418 BAC24022 CAI22379
RNA Seq Atlas 128674