Version 5.4
Mus musculus Gene: Prokr2
Summary
InnateDB Gene IDBG-207366.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prokr2
Gene Name prokineticin receptor 2
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000050558
Encoded Proteins
IDBP-207368
prokineticin receptor 2
IDBP-260865
prokineticin receptor 2
IDBP-260867
prokineticin receptor 2
IDBP-541512
prokineticin receptor 2
IDBP-541489
prokineticin receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101292:
Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:132337733-132385447
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000049997 ENSMUSP00000056659
ENSMUST00000110157 ENSMUSP00000105785
ENSMUST00000110156 ENSMUSP00000105784
ENSMUST00000142766 ENSMUSP00000124526
ENSMUST00000145995 ENSMUSP00000115564
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0004983 neuropeptide Y receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007623 circadian rhythm
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101292
View Gene Order
ENSBTAG00000015872
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
REACT_205036
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_219025
Peptide ligand-binding receptors pathway
REACT_205369
Signaling by GPCR pathway
REACT_214353
Signal Transduction pathway
REACT_209521
G alpha (q) signalling events pathway
REACT_214436
GPCR downstream signaling pathway
REACT_220217
GPCR ligand binding pathway
REACT_208412
Class A/1 (Rhodopsin-like receptors) pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8K458
TrEMBL E0CY28
UniProt Splice Variant
Entrez Gene 246313
UniGene Mm.283777
RefSeq NM_144944
OMIM
CCDS CCDS16773
HPRD
IMGT
MGI ID MGI:2181363
MGI Symbol Prokr2
EMBL AF487279 AK030458 AK041586 AK080980 AL807793 BC043116
GenPept AAH43116 AAM49571 BAC26971 BAC30994 BAC38103 CAM21514
RNA Seq Atlas 246313

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca