Version 5.4
Homo sapiens Gene: NTN4
Summary
InnateDB Gene IDBG-51764.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NTN4
Gene Name netrin 4
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000074527
Encoded Proteins
IDBP-51766
netrin 4
IDBP-51768
netrin 4
IDBP-599189
netrin 4
IDBP-600924
netrin 4
IDBP-588492
netrin 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary NTN4 belongs to a family of proteins related to laminins (see LAMA1, MIM 150320) Koch et al. (2000) [PubMed 11038171].[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:95657807-95791152
Strand Reverse strand
Band q22
Transcripts
ENST00000343702 ENSP00000340998
ENST00000344911 ENSP00000339436
ENST00000538383 ENSP00000444432
ENST00000553059 ENSP00000447292
ENST00000550074
ENST00000552603
ENST00000547980 ENSP00000447594
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043237 laminin-1 binding
Biological Process
GO:0007411 axon guidance
GO:0016322 neuron remodeling
GO:0030198 extracellular matrix organization
GO:0060668 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling
Cellular Component
GO:0005604 basement membrane
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020019
View Gene Order
ENSBTAG00000003183
Not yet available
Pathways
NETPATH
REACTOME
REACT_22237
Netrin-1 signaling pathway
REACT_111045
Developmental Biology pathway
REACT_118779
Extracellular matrix organization pathway
REACT_18266
Axon guidance pathway
REACT_163874
Non-integrin membrane-ECM interactions pathway
KEGG
hsa04360
Axon guidance pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F8W0I7
UniProt Splice Variant
Entrez Gene 59277
UniGene Hs.201034 Hs.630765
RefSeq NM_021229
HUGO HGNC:13658
OMIM 610401
CCDS CCDS9054
HPRD 10121
IMGT
EMBL AC008128 AC090001
GenPept
RNA Seq Atlas 59277

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca