Version 5.4
Homo sapiens Gene: POLQ
Summary
InnateDB Gene IDBG-51980.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POLQ
Gene Name polymerase (DNA directed), theta
Synonyms POLH; PRO0327;
Species Homo sapiens
Ensembl Gene ENSG00000051341
Encoded Proteins
IDBP-51982
polymerase (DNA directed), theta
IDBP-811930
polymerase (DNA directed), theta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:121431427-121546641
Strand Reverse strand
Band q13.33
Transcripts
ENST00000264233 ENSP00000264233
ENST00000474243
ENST00000488282
ENST00000621776 ENSP00000481120
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0043142 single-stranded DNA-dependent ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
Cellular Component
GO:0005654 nucleoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
ENSMUSG00000034206
View Gene Order
Ortholuge
SSD Ortholog
Ortholog supports species divergence
ENSBTAG00000001920
Not yet available
Ortholuge
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt O75417
TrEMBL
UniProt Splice Variant
Entrez Gene 10721
UniGene Hs.241517
RefSeq NM_199420 XM_006713480
HUGO HGNC:9186
OMIM 604419
CCDS CCDS33833
HPRD 10375
IMGT
EMBL AC069239 AC079841 AF043628 AF052573 AY338826
GenPept AAC33565 AAD05272 AAR08421
RNA Seq Atlas 10721

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca