Homo sapiens Gene: ADAMTSL1
Summary
InnateDB Gene IDBG-52228.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTSL1
Gene Name ADAMTS-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000178031
Encoded Proteins
ADAMTS-like 1
ADAMTS-like 1
ADAMTS-like 1
ADAMTS-like 1
ADAMTS-like 1
ADAMTS-like 1
ADAMTS-like 1
ADAMTS-like 1
ADAMTS-like 1
ADAMTS-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:18473894-18910950
Strand Forward strand
Band p22.2
Transcripts
ENST00000327883 ENSP00000327887
ENST00000380570 ENSP00000369944
ENST00000276935 ENSP00000276935
ENST00000380566 ENSP00000369940
ENST00000380559
ENST00000388710 ENSP00000373362
ENST00000380548 ENSP00000369921
ENST00000380545 ENSP00000369918
ENST00000380538 ENSP00000369911
ENST00000431052 ENSP00000401157
ENST00000496521
ENST00000489062
ENST00000546040
ENST00000542621 ENSP00000440472
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Post-translational protein modification pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.522019 Hs.651614 Hs.741483
RefSeq NM_001040272 NM_052866
HUGO
OMIM
CCDS CCDS47954 CCDS6485
HPRD 16462
IMGT
EMBL
GenPept
RNA Seq Atlas