Homo sapiens Protein: ADAMTSL1
Summary
InnateDB Protein IDBP-52080.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAMTSL1
Protein Name ADAMTS-like 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000327887
InnateDB Gene IDBG-52228 (ADAMTSL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted, extracellular space, extracellular matrix {ECO:0000269PubMed:11805097, ECO:0000269PubMed:17395588, ECO:0000269PubMed:19671700}.
Disease Associations
Tissue Specificity Expressed primarily in adult skeletal muscle. {ECO:0000269PubMed:11805097}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000884 Thrombospondin, type 1 repeat
IPR010294 ADAM-TS Spacer 1
IPR013273 Peptidase M12B, ADAM-TS
PFAM PF00090
PF05986
PRINTS PR01857
PIRSF
SMART SM00209
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N6G6
PhosphoSite PhosphoSite-Q8N6G6
TrEMBL
UniProt Splice Variant
Entrez Gene 92949
UniGene Hs.741483
RefSeq NP_443098
HUGO HGNC:14632
OMIM 609198
CCDS CCDS6485
HPRD 16462
IMGT
EMBL AF176313 AF251058 AK092602 AK291956 AL158150 AL353895 AL442638 AL449963 AL591423 AY358327 BC030262 BC100788 BC100790 CH471071
GenPept AAH30262 AAI00789 AAI00791 AAK34948 AAK84170 AAQ88693 BAC03925 BAF84645 CAI14851 CAO03592 EAW58656