Version 5.4
Homo sapiens Gene: APOO
Summary
InnateDB Gene IDBG-52479.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol APOO
Gene Name apolipoprotein O
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184831
Encoded Proteins
IDBP-52481
apolipoprotein O
IDBP-365610
apolipoprotein O
IDBP-585949
apolipoprotein O
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:23833353-23907934
Strand Reverse strand
Band p22.11
Transcripts
ENST00000379226 ENSP00000368528
ENST00000439528 ENSP00000402557
ENST00000476598
ENST00000490078 ENSP00000434341
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006869 lipid transport
Cellular Component
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0016021 integral component of membrane
GO:0034361 very-low-density lipoprotein particle
GO:0034362 low-density lipoprotein particle
GO:0034364 high-density lipoprotein particle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000049233
View Gene Order
ENSBTAG00000010937
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.495851
RefSeq NM_024122 XM_006724516 XM_006724517
HUGO
OMIM
CCDS CCDS14208
HPRD 06657
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca