Homo sapiens Gene: USP34
Summary
InnateDB Gene IDBG-53292.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol USP34
Gene Name ubiquitin specific peptidase 34
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000115464
Encoded Proteins
ubiquitin specific peptidase 34
ubiquitin specific peptidase 34
ubiquitin specific peptidase 34
ubiquitin specific peptidase 34
ubiquitin specific peptidase 34
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 2:61187463-61470769
Strand Reverse strand
Band p15
Transcripts
ENST00000398571 ENSP00000381577
ENST00000411912 ENSP00000398960
ENST00000436269 ENSP00000398489
ENST00000453734 ENSP00000410559
ENST00000453133 ENSP00000388129
ENST00000492604
ENST00000463046
ENST00000490552
ENST00000498268
ENST00000476716
ENST00000467128
ENST00000472689
ENST00000472706
ENST00000490527
ENST00000483672
ENST00000482250
ENST00000487547
ENST00000468703
ENST00000492882
ENST00000484179
ENST00000494867
ENST00000460004
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
Experimentally validated
Total 41 [view]
Protein-Protein 41 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
GO:0004221 ubiquitin thiolesterase activity
GO:0004843 ubiquitin-specific protease activity
GO:0005488 binding
GO:0005515 protein binding
GO:0036459 ubiquitinyl hydrolase activity
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016055 Wnt signaling pathway
GO:0016579 protein deubiquitination
GO:0071108 protein K48-linked deubiquitination
GO:0090263 positive regulation of canonical Wnt signaling pathway
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
Signaling by WNT in cancer pathway
Signaling by Wnt pathway
Signal Transduction pathway
TCF dependent signaling in response to WNT pathway
RNF mutants show enhanced WNT signaling and proliferation pathway
XAV939 inhibits tankyrase, stabilizing AXIN pathway
Disease pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q70CQ2
TrEMBL H7C150
UniProt Splice Variant
Entrez Gene 9736
UniGene Hs.609344 Hs.644708 Hs.714529
RefSeq NM_014709
HUGO HGNC:20066
OMIM 615295
CCDS CCDS42686
HPRD
IMGT
EMBL AB011142 AB018272 AC016727 AC016747 AC016894 AC018889 AJ586138 AK125898 AL050092 AL831918 BC022783 BC062325 BC107761
GenPept AAH22783 AAH62325 AAI07762 BAA25496 BAA34449 BAG54261 CAB43264 CAD38579 CAE51938
RNA Seq Atlas 9736