Version 5.4
Homo sapiens Gene: SYNPO
Summary
InnateDB Gene IDBG-53794.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SYNPO
Gene Name synaptopodin
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171992
Encoded Proteins
IDBP-53798
synaptopodin
IDBP-241994
synaptopodin
IDBP-477665
synaptopodin
IDBP-482846
synaptopodin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008]
Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein\'s associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997 [PubMed 9314539]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:150601080-150659220
Strand Forward strand
Band q33.1
Transcripts
ENST00000307662 ENSP00000302139
ENST00000394243 ENSP00000377789
ENST00000522122 ENSP00000428378
ENST00000518872
ENST00000519664 ENSP00000429268
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
Biological Process
GO:0032233 positive regulation of actin filament bundle assembly
GO:0051492 regulation of stress fiber assembly
Cellular Component
GO:0001725 stress fiber
GO:0005737 cytoplasm
GO:0005923 tight junction
GO:0014069 postsynaptic density
GO:0015629 actin cytoskeleton
GO:0043197 dendritic spine
GO:0043204 perikaryon
GO:0045211 postsynaptic membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000043079
View Gene Order
ENSBTAG00000013744
Not yet available
Cross-References
SwissProt Q8N3V7
TrEMBL A7MD96 Q71HJ6
UniProt Splice Variant
Entrez Gene 11346
UniGene Hs.435228
RefSeq NM_001109974 NM_001166208 NM_001166209 NM_007286 XM_005268369 XM_005268370 XM_005268371 XM_006714755
HUGO HGNC:30672
OMIM 608155
CCDS CCDS4308 CCDS54937 CCDS54938
HPRD
IMGT
EMBL AB028952 AF499136 AF499137 AF499138 AK127049 AK290178 AL831818 BC142683 BC146665 BC152538 CH471062 Y11072
GenPept AAI42684 AAI46666 AAI52539 AAQ07402 AAQ07403 AAQ07404 BAA82981 BAF82867 CAA71955 CAD38532 EAW61715 EAW61716
RNA Seq Atlas 11346

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca