Version 5.4
Homo sapiens Gene: OSBPL11
Summary
InnateDB Gene IDBG-54220.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSBPL11
Gene Name oxysterol binding protein-like 11
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000144909
Encoded Proteins
IDBP-54222
oxysterol binding protein-like 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:125528858-125595090
Strand Reverse strand
Band q21.2
Transcripts
ENST00000296220 ENSP00000296220
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
Biological Process
GO:0006869 lipid transport
GO:0010890 positive regulation of sequestering of triglyceride
GO:0045444 fat cell differentiation
Cellular Component
GO:0005794 Golgi apparatus
GO:0031902 late endosome membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000022807
View Gene Order
ENSBTAG00000006471
Not yet available
Cross-References
SwissProt Q9BXB4
TrEMBL Q9GZM0
UniProt Splice Variant
Entrez Gene 114885
UniGene Hs.477440 Hs.701305
RefSeq NM_022776
HUGO HGNC:16397
OMIM 606739
CCDS CCDS3033
HPRD
IMGT
EMBL AF346292 AF392454 AK023074 AK023226 AK292702 BC010422 BC065213 CH471052
GenPept AAH10422 AAH65213 AAK31141 AAL40667 BAB14391 BAB14477 BAF85391 EAW79389
RNA Seq Atlas 114885

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca