Version 5.4
Homo sapiens Gene: NUAK1
Summary
InnateDB Gene IDBG-54705.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUAK1
Gene Name NUAK family, SNF1-like kinase, 1
Synonyms ARK5
Species Homo sapiens
Ensembl Gene ENSG00000074590
Encoded Proteins
IDBP-54707
NUAK family, SNF1-like kinase, 1
IDBP-589140
NUAK family, SNF1-like kinase, 1
IDBP-596147
NUAK family, SNF1-like kinase, 1
IDBP-594498
NUAK family, SNF1-like kinase, 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:106063340-106140033
Strand Reverse strand
Band q23.3
Transcripts
ENST00000261402 ENSP00000261402
ENST00000553094 ENSP00000446873
ENST00000549704 ENSP00000449990
ENST00000548902 ENSP00000448288
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 27 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002039 p53 binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0006974 cellular response to DNA damage stimulus
GO:0007155 cell adhesion
GO:0008152 metabolic process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0030155 regulation of cell adhesion
GO:0035507 regulation of myosin-light-chain-phosphatase activity
GO:0042127 regulation of cell proliferation
GO:2000772 regulation of cellular senescence
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000020032
View Gene Order
ENSBTAG00000010457
Not yet available
Cross-References
SwissProt O60285
TrEMBL A0A024RBL3 F8VSH4 F8VXF0 F8VZ96
UniProt Splice Variant
Entrez Gene 9891
UniGene Hs.524692 Hs.727337 Hs.743544
RefSeq NM_014840
HUGO HGNC:14311
OMIM 608130
CCDS CCDS31892
HPRD
IMGT
EMBL AB011109 AC010182 AC011595 AK027302 AK289992 BC152462 CH471054
GenPept AAI52463 BAA25463 BAB55026 BAF82681 EAW97768 EAW97769
RNA Seq Atlas 9891

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca