Homo sapiens Gene: DND1
Summary
InnateDB Gene IDBG-547469.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DND1
Gene Name dead end homolog 1 (zebrafish)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000256453
Encoded Proteins
dead end homolog 1 (zebrafish)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:140670794-140673586
Strand Reverse strand
Band q31.3
Transcripts
ENST00000542735 ENSP00000445366
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0017091 AU-rich element binding
Biological Process
GO:0007275 multicellular organismal development
GO:0007281 germ cell development
GO:0060965 negative regulation of gene silencing by miRNA
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q8IYX4
TrEMBL
UniProt Splice Variant
Entrez Gene 373863
UniGene Hs.446891 Hs.585785 Hs.591262 Hs.608636 Hs.741051
RefSeq NM_194249
HUGO HGNC:23799
OMIM 609385
CCDS CCDS4236
HPRD 13240
IMGT
EMBL AY321065 BC033496
GenPept AAH33496 AAQ63635
RNA Seq Atlas 373863