Homo sapiens Gene: PLXNA1
Summary
InnateDB Gene IDBG-54782.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLXNA1
Gene Name plexin A1
Synonyms NOV; NOVP; PLEXIN-A1; PLXN1;
Species Homo sapiens
Ensembl Gene ENSG00000114554
Encoded Proteins
plexin A1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 3:126988594-127037392
Strand Forward strand
Band q21.3
Transcripts
ENST00000393409 ENSP00000377061
ENST00000503234
ENST00000503363
ENST00000505278
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0017154 semaphorin receptor activity
Biological Process
GO:0007165 signal transduction
GO:0007275 multicellular organismal development
GO:0007411 axon guidance
GO:0014910 regulation of smooth muscle cell migration
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching
GO:0071526 semaphorin-plexin signaling pathway
Cellular Component
GO:0002116 semaphorin receptor complex
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Developmental Biology pathway
Semaphorin interactions pathway
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion pathway
Other semaphorin interactions pathway
Axon guidance pathway
CRMPs in Sema3A signaling pathway
Sema3A PAK dependent Axon repulsion pathway
KEGG
Axon guidance pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q9UIW2
TrEMBL B3KY38 B4DE20 F8VSZ4 Q9NSM6
UniProt Splice Variant
Entrez Gene 5361
UniGene Hs.432329 Hs.623489
RefSeq NM_032242 XM_006713663
HUGO HGNC:9099
OMIM 601055
CCDS CCDS33847
HPRD 11868
IMGT
EMBL AC011199 AK128612 AK293425 AL162013 X87832
GenPept BAG54700 BAG56931 CAB57274 CAB82365
RNA Seq Atlas 5361