Version 5.4
Homo sapiens Gene: PLAA
Summary
InnateDB Gene IDBG-54945.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLAA
Gene Name phospholipase A2-activating protein
Synonyms DOA1; PLA2P; PLAP
Species Homo sapiens
Ensembl Gene ENSG00000137055
Encoded Proteins
IDBP-235671
phospholipase A2-activating protein
IDBP-475556
phospholipase A2-activating protein
IDBP-481550
phospholipase A2-activating protein
IDBP-478776
phospholipase A2-activating protein
IDBP-481504
phospholipase A2-activating protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:26904083-26947463
Strand Reverse strand
Band p21.2
Transcripts
ENST00000397292 ENSP00000380460
ENST00000517642 ENSP00000430447
ENST00000487173 ENSP00000430734
ENST00000520884 ENSP00000429372
ENST00000520641
ENST00000521968
ENST00000523212 ENSP00000428111
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 33 [view]
Protein-Protein 30 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
GO:0016005 phospholipase A2 activator activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006954 inflammatory response
GO:0007165 signal transduction
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028577
View Gene Order
ENSBTAG00000013011
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q9Y263
TrEMBL E5RIM3
UniProt Splice Variant
Entrez Gene 9373
UniGene Hs.27182 Hs.595012
RefSeq NM_001031689
HUGO HGNC:9043
OMIM 603873
CCDS CCDS35000
HPRD
IMGT
EMBL AF083395 AF145020 AJ238243 AK001642 AK002143 AK223544 AL133608 AL356133 BC032551
GenPept AAD03030 AAD42075 AAH32551 BAA91803 BAA92105 BAD97264 CAB42881 CAB63739 CAH72641
RNA Seq Atlas 9373

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca