Homo sapiens Gene: PCYOX1
Summary
InnateDB Gene IDBG-55265.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCYOX1
Gene Name prenylcysteine oxidase 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116005
Encoded Proteins
prenylcysteine oxidase 1
prenylcysteine oxidase 1
prenylcysteine oxidase 1
prenylcysteine oxidase 1
prenylcysteine oxidase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Prenylcysteine is released during the degradation of prenylated proteins. PCYOX1 catalyzes the degradation of prenylcysteine to yield free cysteines and a hydrophobic isoprenoid product (Tschantz et al., 1999 [PubMed 10585463]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:70257386-70281191
Strand Forward strand
Band p13.3
Transcripts
ENST00000264441 ENSP00000264441
ENST00000422380 ENSP00000404327
ENST00000414812 ENSP00000413178
ENST00000433351 ENSP00000387654
ENST00000451279 ENSP00000408751
ENST00000480949
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0001735 prenylcysteine oxidase activity
GO:0008555 chloride-transporting ATPase activity
GO:0016491 oxidoreductase activity
GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor
Biological Process
GO:0006821 chloride transport
GO:0030327 prenylated protein catabolic process
GO:0030328 prenylcysteine catabolic process
GO:0030329 prenylcysteine metabolic process
GO:0055114 oxidation-reduction process
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0005764 lysosome
GO:0005886 plasma membrane
GO:0034361 very-low-density lipoprotein particle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Terpenoid backbone biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.567502 Hs.606863 Hs.639218
RefSeq NM_016297
HUGO
OMIM
CCDS CCDS1902
HPRD 11422
IMGT
EMBL
GenPept
RNA Seq Atlas