Version 5.4
Homo sapiens Gene: CMKLR1
Summary
InnateDB Gene IDBG-55274.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CMKLR1
Gene Name chemokine-like receptor 1
Synonyms CHEMERINR; ChemR23; DEZ; RVER1
Species Homo sapiens
Ensembl Gene ENSG00000174600
Encoded Proteins
IDBP-55276
chemokine-like receptor 1
IDBP-382607
chemokine-like receptor 1
IDBP-585387
chemokine-like receptor 1
IDBP-592942
chemokine-like receptor 1
IDBP-590471
chemokine-like receptor 1
IDBP-594035
chemokine-like receptor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:108288044-108339341
Strand Reverse strand
Band q23.3
Transcripts
ENST00000312143 ENSP00000311733
ENST00000412676 ENSP00000401293
ENST00000552995 ENSP00000447579
ENST00000550402 ENSP00000449716
ENST00000550573 ENSP00000448925
ENST00000549466 ENSP00000448362
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0001501 skeletal system development
GO:0006935 chemotaxis
GO:0006955 immune response
GO:0007186 G-protein coupled receptor signaling pathway
GO:0010759 positive regulation of macrophage chemotaxis
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032695 negative regulation of interleukin-12 production
GO:0045600 positive regulation of fat cell differentiation
GO:0050848 regulation of calcium-mediated signaling
GO:0070098 chemokine-mediated signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042190
View Gene Order
ENSBTAG00000022039
Not yet available
Cross-References
SwissProt Q99788
TrEMBL
UniProt Splice Variant
Entrez Gene 1240
UniGene Hs.197143
RefSeq NM_004072 NM_001142343 NM_001142344 NM_001142345
HUGO HGNC:2121
OMIM 602351
CCDS CCDS41829 CCDS44965
HPRD 03829
IMGT
EMBL AB065871 AC009729 AC063957 AK291800 AY497547 BC106927 BC106928 BT019556 BT019557 CH471054 U79526 U79527 Y14838
GenPept AAC51258 AAC51259 AAI06928 AAI06929 AAR90850 AAV38363 AAV38364 BAC06089 BAF84489 CAA75112 EAW97810 EAW97811
RNA Seq Atlas 1240

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca