Version 5.4
Homo sapiens Gene: SOX30
Summary
InnateDB Gene IDBG-55601.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOX30
Gene Name SRY (sex determining region Y)-box 30
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000039600
Encoded Proteins
IDBP-55603
SRY (sex determining region Y)-box 30
IDBP-55605
SRY (sex determining region Y)-box 30
IDBP-483577
SRY (sex determining region Y)-box 30
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the differentiation of developing male germ cells. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:157625679-157671480
Strand Reverse strand
Band q33.3
Transcripts
ENST00000265007 ENSP00000265007
ENST00000311371 ENSP00000309343
ENST00000519442 ENSP00000427984
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0007283 spermatogenesis
GO:0031960 response to corticosteroid
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000040489
View Gene Order
ENSBTAG00000020491
Not yet available
Cross-References
SwissProt O94993
TrEMBL B4DXW7
UniProt Splice Variant
Entrez Gene 11063
UniGene Hs.529462
RefSeq NM_007017 NM_178424
HUGO HGNC:30635
OMIM 606698
CCDS CCDS4339 CCDS4340
HPRD
IMGT
EMBL AB022083 AB022441 AC008694 AK302162 BC033492
GenPept AAH33492 BAA37146 BAA37149 BAG63529
RNA Seq Atlas 11063

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca