Version 5.4
Homo sapiens Protein: SOX30
Summary
InnateDB Protein IDBP-55605.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SOX30
Protein Name SRY (sex determining region Y)-box 30
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000309343
InnateDB Gene IDBG-55601 (SOX30)
Protein Structure
UniProt Annotation
Function Transcriptional activator. Binds to the DNA sequence 5'- ACAAT-3' and shows a preference for guanine residues surrounding this core motif. {ECO:0000269PubMed:10359848}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00267, ECO:0000269PubMed:10359848}.
Disease Associations
Tissue Specificity Expressed in testis. {ECO:0000269PubMed:10359848}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0031960 response to corticosteroid
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009071 High mobility group box domain
PFAM PF00505
PF09011
PRINTS
PIRSF
SMART SM00398
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94993
PhosphoSite PhosphoSite-O94993
TrEMBL
UniProt Splice Variant
Entrez Gene 11063
UniGene Hs.529462
RefSeq NP_008948
HUGO HGNC:30635
OMIM 606698
CCDS CCDS4340
HPRD 09461
IMGT
EMBL AB022083 AB022441 BC033492
GenPept AAH33492 BAA37146 BAA37149

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca