Version 5.4
Homo sapiens Gene: FIBP
Summary
InnateDB Gene IDBG-57983.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FIBP
Gene Name fibroblast growth factor (acidic) intracellular binding protein
Synonyms FGFIBP; FIBP-1
Species Homo sapiens
Ensembl Gene ENSG00000172500
Encoded Proteins
IDBP-57985
fibroblast growth factor (acidic) intracellular binding protein
IDBP-57987
fibroblast growth factor (acidic) intracellular binding protein
IDBP-586466
fibroblast growth factor (acidic) intracellular binding protein
IDBP-595303
fibroblast growth factor (acidic) intracellular binding protein
IDBP-584882
fibroblast growth factor (acidic) intracellular binding protein
IDBP-587000
fibroblast growth factor (acidic) intracellular binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:65883741-65888539
Strand Reverse strand
Band q13.1
Transcripts
ENST00000338369 ENSP00000344572
ENST00000357519 ENSP00000350124
ENST00000426652
ENST00000442885
ENST00000534032
ENST00000525765
ENST00000531115 ENSP00000431457
ENST00000533045 ENSP00000434043
ENST00000533037 ENSP00000431414
ENST00000532934
ENST00000532229 ENSP00000433683
ENST00000532679
ENST00000528937
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0017134 fibroblast growth factor binding
Biological Process
GO:0008543 fibroblast growth factor receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000024911
View Gene Order
ENSBTAG00000020775
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_004214 NM_198897 XM_005274391 XM_005274392
HUGO
OMIM
CCDS CCDS8118 CCDS8119
HPRD 08492
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca