Version 5.4
Homo sapiens Protein: FIBP
Summary
InnateDB Protein IDBP-57987.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FIBP
Protein Name fibroblast growth factor (acidic) intracellular binding protein
Synonyms FGFIBP; FIBP-1;
Species Homo sapiens
Ensembl Protein ENSP00000350124
InnateDB Gene IDBG-57983 (FIBP)
Protein Structure
UniProt Annotation
Function May be involved in mitogenic function of FGF1.
Subcellular Localization Nucleus. Endomembrane system; Peripheral membrane protein. Note=Also associated with cytoplasmic membranes, particularly of mitochondria.
Disease Associations
Tissue Specificity Highly expressed in heart, skeletal muscle and pancreas. Expressed at lower levels in brain. Also found in placenta, liver and kidney.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0017134 fibroblast growth factor binding
Biological Process
GO:0008543 fibroblast growth factor receptor signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0012505 endomembrane system
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR008614 Acidic fibroblast growth factor binding
PFAM PF05427
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O43427
PhosphoSite PhosphoSite-O43427
TrEMBL B4DKH9
UniProt Splice Variant
Entrez Gene 9158
UniGene
RefSeq NP_004205
HUGO HGNC:3705
OMIM 608296
CCDS CCDS8118
HPRD 08492
IMGT
EMBL AF010187 AF171944 AF171945 AF171946 AF250391 AF250392 AK289562 AK296571 BC014388 BC017448 CH471076 CR456749 DQ388430
GenPept AAC97140 AAD51694 AAD51695 AAD51696 AAG01396 AAG01397 AAH14388 AAH17448 ABD48957 BAF82251 BAG59191 CAG33030 EAW74465 EAW74466

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca