Homo sapiens Gene: REG1A
Summary
InnateDB Gene IDBG-58452.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REG1A
Gene Name regenerating islet-derived 1 alpha
Synonyms ICRF; P19; PSP; PSPS; PSPS1; PTP; REG;
Species Homo sapiens
Ensembl Gene ENSG00000115386
Encoded Proteins
regenerating islet-derived 1 alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:79120362-79123419
Strand Forward strand
Band p12
Transcripts
ENST00000233735 ENSP00000233735
ENST00000488524
ENST00000461579
ENST00000485184
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0030246 carbohydrate binding
Biological Process
GO:0008284 positive regulation of cell proliferation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.49407
RefSeq NM_002909
HUGO
OMIM
CCDS CCDS1964
HPRD 01338
IMGT
EMBL
GenPept
RNA Seq Atlas