Version 5.4
Homo sapiens Gene: EPN3
Summary
InnateDB Gene IDBG-58726.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EPN3
Gene Name epsin 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000049283
Encoded Proteins
IDBP-58728
epsin 3
IDBP-481001
epsin 3
IDBP-485062
epsin 3
IDBP-482483
epsin 3
IDBP-484212
epsin 3
IDBP-476652
epsin 3
IDBP-475342
epsin 3
IDBP-484429
epsin 3
IDBP-479317
epsin 3
IDBP-476920
epsin 3
IDBP-588164
epsin 3
IDBP-758361
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:50532543-50543750
Strand Forward strand
Band q21.33
Transcripts
ENST00000268933 ENSP00000268933
ENST00000503246 ENSP00000426762
ENST00000503690 ENSP00000424306
ENST00000514874 ENSP00000422682
ENST00000510462
ENST00000515028
ENST00000507998
ENST00000512291 ENSP00000421936
ENST00000512379 ENSP00000422201
ENST00000510045 ENSP00000421933
ENST00000504857
ENST00000507709 ENSP00000426676
ENST00000511414
ENST00000515126 ENSP00000422601
ENST00000507467 ENSP00000421515
ENST00000537145 ENSP00000439512
ENST00000574464 ENSP00000460911
ENST00000571402
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0008289 lipid binding
GO:1990175 EH domain binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005905 coated pit
GO:0019897 extrinsic component of plasma membrane
GO:0030136 clathrin-coated vesicle
GO:0048471 perinuclear region of cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000010080
View Gene Order
ENSBTAG00000015893
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
hsa04144
Endocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 55040
UniGene Hs.670090 Hs.740136
RefSeq NM_017957
HUGO HGNC:18235
OMIM 607264
CCDS CCDS11570
HPRD 06272
IMGT
EMBL
GenPept
RNA Seq Atlas 55040

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca