Homo sapiens Gene: DCAF12
Summary
InnateDB Gene IDBG-59129.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCAF12
Gene Name DDB1 and CUL4 associated factor 12
Synonyms CT102; KIAA1892; TCC52; WDR40A
Species Homo sapiens
Ensembl Gene ENSG00000198876
Encoded Proteins
DDB1 and CUL4 associated factor 12
DDB1 and CUL4 associated factor 12
DDB1 and CUL4 associated factor 12
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:34086387-34127399
Strand Reverse strand
Band p13.3
Transcripts
ENST00000361264 ENSP00000355114
ENST00000396990 ENSP00000380187
ENST00000450964 ENSP00000415833
ENST00000466402
ENST00000463286
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL X6RBJ8
UniProt Splice Variant
Entrez Gene 25853
UniGene Hs.741270
RefSeq NM_015397 XM_006716752
HUGO HGNC:19911
OMIM
CCDS CCDS6549
HPRD 10031
IMGT
EMBL AL354989
GenPept
RNA Seq Atlas 25853