|Homo sapiens Gene: FOXA2|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||forkhead box A2|
forkhead box A2
forkhead box A2
|Useful resources||Stemformatics EHFPI ImmGen|
FOXA2 is expressed selectively in the respiratory epithelium where it plays a critical role in regulating genetic programs influencing Th2 cell-mediated pulmonary inflammation.
|InnateDB Annotation from Orthologs|
[Mus musculus] Foxa2 is expressed selectively in the respiratory epithelium where it plays a critical role in regulating genetic programs influencing Th2 cell-mediated pulmonary inflammation.
This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]
|Genomic Location||Chromosome 20:22581005-22585455|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Developmental Biology pathway
Regulation of beta-cell development pathway
Regulation of gene expression in beta cells pathway
Maturity onset diabetes of the young pathway
FOXA2 and FOXA3 transcription factor networks
FOXA transcription factor networks
Hedgehog signaling events mediated by Gli proteins
FOXA1 transcription factor network
|UniProt Splice Variant|
|RefSeq||NM_153675 XM_006723562 NM_021784|
|EMBL||AB028021 AF147787 AF176110 AL121722 BC006545 BC011780 BC019288|
|GenPept||AAD41081 AAD51978 AAH06545 AAH11780 AAH19288 BAA78106 CAB89773|
|RNA Seq Atlas||3170|