Version 5.4
Homo sapiens Gene: KSR2
Summary
InnateDB Gene IDBG-59577.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KSR2
Gene Name kinase suppressor of ras 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000171435
Encoded Proteins
IDBP-59579
kinase suppressor of ras 2
IDBP-383868
kinase suppressor of ras 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 12:117453012-117968983
Strand Reverse strand
Band q24.23
Transcripts
ENST00000339824 ENSP00000339952
ENST00000425217 ENSP00000389715
ENST00000545002
ENST00000543793
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005078 MAP-kinase scaffold activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0031434 mitogen-activated protein kinase kinase binding
GO:0046872 metal ion binding
Biological Process
GO:0006468 protein phosphorylation
GO:0019722 calcium-mediated signaling
GO:0035556 intracellular signal transduction
GO:0043410 positive regulation of MAPK cascade
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000061578
View Gene Order
ENSBTAG00000044119
Not yet available
Cross-References
SwissProt
TrEMBL E9PB13
UniProt Splice Variant
Entrez Gene 283455
UniGene Hs.375836 Hs.641999
RefSeq NM_173598 XM_006719357
HUGO HGNC:18610
OMIM 610737
CCDS CCDS61250
HPRD 13952
IMGT
EMBL AC073864 AC079127 AC084291 AC092936 AC127166
GenPept
RNA Seq Atlas 283455

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca