Version 5.4
Homo sapiens Gene: PRELID1
Summary
InnateDB Gene IDBG-59784.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRELID1
Gene Name PRELI domain containing 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000169230
Encoded Proteins
IDBP-59786
PRELI domain containing 1
IDBP-476644
PRELI domain containing 1
IDBP-477218
PRELI domain containing 1
IDBP-482839
PRELI domain containing 1
IDBP-475132
PRELI domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the late embryogenesis abundant motif-containing protein family. The encoded protein is localized to mitochondria and may function as a cytoprotectant by regulating cell death and differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. Several related pseudogenes have been identified. [provided by RefSeq, Nov 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:177303774-177306959
Strand Forward strand
Band q35.3
Transcripts
ENST00000303204 ENSP00000302114
ENST00000511309
ENST00000510797 ENSP00000423873
ENST00000504594 ENSP00000421657
ENST00000503216 ENSP00000427097
ENST00000502670
ENST00000503853 ENSP00000426351
ENST00000510701
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:1990050 phosphatidic acid transporter activity
Biological Process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006955 immune response
GO:0007275 multicellular organismal development
GO:0010917 negative regulation of mitochondrial membrane potential
GO:0010950 positive regulation of endopeptidase activity
GO:0015914 phospholipid transport
GO:0043066 negative regulation of apoptotic process
GO:0045580 regulation of T cell differentiation
GO:0051881 regulation of mitochondrial membrane potential
GO:0070234 positive regulation of T cell apoptotic process
GO:0090201 negative regulation of release of cytochrome c from mitochondria
GO:0097035 regulation of membrane lipid distribution
GO:1901857 positive regulation of cellular respiration
GO:1902511 negative regulation of apoptotic DNA fragmentation
GO:2001140 positive regulation of phospholipid transport
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000021486
View Gene Order
ENSBTAG00000005009
Not yet available
Cross-References
SwissProt
TrEMBL D6RC47
UniProt Splice Variant
Entrez Gene 27166
UniGene
RefSeq NM_001271828 NM_013237
HUGO HGNC:30255
OMIM 605733
CCDS CCDS4415 CCDS64328
HPRD 16149
IMGT
EMBL AC146507
GenPept
RNA Seq Atlas 27166

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca