Version 5.4
| Homo sapiens Gene: SULT2A1 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-59884.5 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | SULT2A1 | ||||||||||||||||||
| Gene Name | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | ||||||||||||||||||
| Synonyms | DHEA-ST; DHEAS; HST; hSTa; ST2; ST2A1; ST2A3; STD | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000105398 | ||||||||||||||||||
| Encoded Proteins |
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a member of the sulfotransferase family. Sulfotransferases aid in the metabolism of drugs and endogenous compounds by converting these substances into more hydrophilic water-soluble sulfate conjugates that can be easily excreted. This protein catalyzes the sulfation of steroids and bile acids in the liver and adrenal glands, and may have a role in the inherited adrenal androgen excess in women with polycystic ovary syndrome. [provided by RefSeq, Mar 2010] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 19:47870466-47886397 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q13.33 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
| No orthologs found for this gene | |||||||||||||||||||
| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Cytosolic sulfonation of small molecules pathway
Metabolism of lipids and lipoproteins pathway
Phase II conjugation pathway
Metabolism pathway
Biological oxidations pathway
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| KEGG |
Metabolism of xenobiotics by cytochrome P450 pathway
Bile secretion pathway
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| INOH | |||||||||||||||||||
| PID NCI |
E2F transcription factor network
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| Cross-References | |||||||||||||||||||
| SwissProt | Q06520 | ||||||||||||||||||
| TrEMBL | A8K015 | ||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 6822 | ||||||||||||||||||
| UniGene | Hs.515835 | ||||||||||||||||||
| RefSeq | NM_003167 | ||||||||||||||||||
| HUGO | HGNC:11458 | ||||||||||||||||||
| OMIM | 125263 | ||||||||||||||||||
| CCDS | CCDS12707 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AK289380 AK313415 BC020755 CH471126 EU522670 L20000 L36191 L36192 L36193 L36194 L36195 L36196 S43859 U08024 U08025 U13056 U13057 U13058 U13059 U13060 U13061 X70222 X84816 | ||||||||||||||||||
| GenPept | AAA17749 AAA17750 AAA35758 AAA75491 AAB23169 AAC51353 AAH20755 ACB21041 BAF82069 BAG36209 CAA49755 CAA59274 EAW57516 | ||||||||||||||||||
| RNA Seq Atlas | 6822 | ||||||||||||||||||