Homo sapiens Gene: PFN3
Summary
InnateDB Gene IDBG-59926.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PFN3
Gene Name profilin 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000196570
Encoded Proteins
profilin 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The product of this gene belongs to the profilin family of proteins. This protein binds to actin and affects the structure of the cytoskeleton. It also may be involved in spermatogenesis. It is a single exon gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:177400107-177400636
Strand Reverse strand
Band q35.3
Transcripts
ENST00000358571 ENSP00000351379
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008289 lipid binding
Biological Process
GO:0030036 actin cytoskeleton organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Regulation of actin cytoskeleton pathway
Shigellosis pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt P60673
TrEMBL
UniProt Splice Variant
Entrez Gene 345456
UniGene Hs.130196
RefSeq NM_001029886
HUGO HGNC:18627
OMIM 612812
CCDS CCDS34301
HPRD
IMGT
EMBL AC090063 BC132952 BC132954 CH471195
GenPept AAI32953 AAI32955 EAW85006
RNA Seq Atlas 345456