Homo sapiens Gene: CST9
Summary
InnateDB Gene IDBG-60077.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CST9
Gene Name cystatin 9 (testatin)
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173335
Encoded Proteins
cystatin 9 (testatin)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted protein that may play a role in hematopoietic differentiation or inflammation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:23602410-23605876
Strand Reverse strand
Band p11.21
Transcripts
ENST00000376971 ENSP00000366170
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004869 cysteine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q5W186
TrEMBL
UniProt Splice Variant
Entrez Gene 128822
UniGene Hs.698020
RefSeq NM_001008693
HUGO HGNC:13261
OMIM
CCDS CCDS33450
HPRD
IMGT
EMBL AF494536 AL121894 BC137302 BC137303
GenPept AAI37303 AAI37304 AAM18055 CAH71437
RNA Seq Atlas 128822