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InnateDB Protein
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IDBP-60079.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CST9
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Protein Name
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cystatin 9 (testatin)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000366170
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InnateDB Gene
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IDBG-60077 (CST9)
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Protein Structure
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| Function |
May play a role in hematopoietic differentiation or inflammation.
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| Subcellular Localization |
Secreted {ECO:0000269PubMed:12535658}. Note=May be targeted through the Golgi via the secretory pathway.
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| Disease Associations |
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| Tissue Specificity |
Expressed in heart, placenta, lung, liver, skeletal muscle and pancreas. Not expressed in brain. Barely expressed in tumor cell lines except for breast adenocarcinoma MCF-7 cells and U-251MG cells. {ECO:0000269PubMed:12535658}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
1
[view]
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| Protein-Protein |
0
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| Protein-DNA |
1
[view]
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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Molecular Function |
| Accession |
GO Term |
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GO:0004869
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cysteine-type endopeptidase inhibitor activity
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| Biological Process |
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GO:0010951
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negative regulation of endopeptidase activity
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR000010
Proteinase inhibitor I25, cystatin
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| PFAM |
PF00031
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| PRINTS |
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| PIRSF |
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| SMART |
SM00043
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| TIGRFAMs |
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| Modification |
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| SwissProt |
Q5W186
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
128822
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| UniGene |
Hs.698020
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| RefSeq |
NP_001008693
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| HUGO |
HGNC:13261
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| OMIM |
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| CCDS |
CCDS33450
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| HPRD |
16768
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| IMGT |
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| EMBL |
AF494536
AL121894
BC137302
BC137303
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| GenPept |
AAI37303
AAI37304
AAM18055
CAH71437
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Version 5.4