|Homo sapiens Gene: CST7|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||cystatin F (leukocystatin)|
cystatin F (leukocystatin)
|Useful resources||Stemformatics EHFPI ImmGen|
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors. [provided by RefSeq, Jul 2008]
|Genomic Location||Chromosome 20:24949230-24959928|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Possible paralog/unusual divergence/ gene prediction error
|UniProt Splice Variant|
|EMBL||AB015225 AB029636 AF031824 AF036342 AJ510167 AJ510168 AJ510169 AJ510170 AL035661 BC015507 BT009825 CR541860 CR541878|
|GenPept||AAC35747 AAC39788 AAH15507 AAP88827 BAA34941 BAB11886 CAB75498 CAD52872 CAG46658 CAG46676|
|RNA Seq Atlas||8530|