Homo sapiens Gene: HSD17B14
Summary
InnateDB Gene IDBG-61250.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HSD17B14
Gene Name hydroxysteroid (17-beta) dehydrogenase 14
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000087076
Encoded Proteins
hydroxysteroid (17-beta) dehydrogenase 14
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary 17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:48813017-48836678
Strand Reverse strand
Band q13.33
Transcripts
ENST00000263278 ENSP00000263278
ENST00000595764 ENSP00000469557
ENST00000599157 ENSP00000472746
ENST00000596349 ENSP00000471631
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004303 estradiol 17-beta-dehydrogenase activity
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity
GO:0050662 coenzyme binding
Biological Process
GO:0006706 steroid catabolic process
GO:0008152 metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q9BPX1
TrEMBL
UniProt Splice Variant
Entrez Gene 51171
UniGene
RefSeq NM_016246
HUGO HGNC:23238
OMIM 612832
CCDS CCDS12736
HPRD 16801
IMGT
EMBL AF126781 AY358430 BC006283 BC006294
GenPept AAF06940 AAH06283 AAH06294 AAQ88796
RNA Seq Atlas 51171