Version 5.4
Homo sapiens Gene: NUCB1
Summary
InnateDB Gene IDBG-61423.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUCB1
Gene Name nucleobindin 1
Synonyms CALNUC; NUC
Species Homo sapiens
Ensembl Gene ENSG00000104805
Encoded Proteins
IDBP-294031
nucleobindin 1
IDBP-294037
nucleobindin 1
IDBP-382981
nucleobindin 1
IDBP-382983
nucleobindin 1
IDBP-382985
nucleobindin 1
IDBP-382986
nucleobindin 1
IDBP-382988
nucleobindin 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:48900050-48923372
Strand Forward strand
Band q13.33
Transcripts
ENST00000405315 ENSP00000385923
ENST00000407032 ENSP00000385211
ENST00000452087 ENSP00000389007
ENST00000443560 ENSP00000397608
ENST00000411700 ENSP00000410519
ENST00000451312 ENSP00000397201
ENST00000424608 ENSP00000389734
ENST00000485798
ENST00000465524
ENST00000460125
ENST00000469291
ENST00000492367
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 27 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005615 extracellular space
GO:0005793 endoplasmic reticulum-Golgi intermediate compartment
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030824
View Gene Order
ENSBTAG00000002378
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.631602
RefSeq NM_006184
HUGO
OMIM
CCDS CCDS12740
HPRD 03205
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca