Homo sapiens Gene: PPM1E | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Summary | |||||||||||||||||||
InnateDB Gene | IDBG-61523.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | PPM1E | ||||||||||||||||||
Gene Name | protein phosphatase, Mg2+/Mn2+ dependent, 1E | ||||||||||||||||||
Synonyms | caMKN; CaMKP-N; POPX1; PP2CH | ||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000175175 | ||||||||||||||||||
Encoded Proteins |
protein phosphatase, Mg2+/Mn2+ dependent, 1E
|
||||||||||||||||||
Protein Structure | |||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5\'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] |
||||||||||||||||||
Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 17:58755869-58985176 | ||||||||||||||||||
Strand | Forward strand | ||||||||||||||||||
Band | q22 | ||||||||||||||||||
Transcripts |
|
||||||||||||||||||
Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
|
||||||||||||||||||
Gene Ontology | |||||||||||||||||||
Molecular Function |
|
||||||||||||||||||
Biological Process |
|
||||||||||||||||||
Cellular Component |
|
||||||||||||||||||
Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
|
Gene ID
Gene Order
Not yet available
|
||||||||||||||||||
Cross-References | |||||||||||||||||||
SwissProt | Q8WY54 | ||||||||||||||||||
TrEMBL | A7E2X1 | ||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 22843 | ||||||||||||||||||
UniGene | Hs.245044 | ||||||||||||||||||
RefSeq | NM_014906 XM_005257169 | ||||||||||||||||||
HUGO | HGNC:19322 | ||||||||||||||||||
OMIM | |||||||||||||||||||
CCDS | CCDS11613 | ||||||||||||||||||
HPRD | |||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AB028995 AC025521 AC100832 AF260269 AF520614 AK289966 BC136290 BC151228 CH471109 CR749253 DA497512 DA791319 | ||||||||||||||||||
GenPept | AAF70325 AAI36291 AAI51229 AAM76058 BAA83024 BAF82655 CAH18109 EAW94429 | ||||||||||||||||||
RNA Seq Atlas | 22843 | ||||||||||||||||||